The Best Supplements to Support Your Routine on GLP-1 Medication

nutriGLP-1 medications such as Mounjaro, Wegovy and Ozempic are helping many people with weight management and improved health in 2025. Alongside these treatments, some people choose to add supplements to their daily routine for extra support with hydration, energy, and overall wellbeing. While supplements are not essential, the right ones can make your journey smoother. Always check with a healthcare professional before starting anything new, but here are some popular options you can easily find online.

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Electrolytes & Hydration

Hydration is one of the most important areas to focus on when taking GLP-1 medication. Electrolyte powders that contain sodium, potassium and magnesium help maintain balance and prevent fatigue. We recommend these Wellgard Electromight electrolyte powders that mix easily with water and are ideal for daily use. Unlike others they actually taste good too.

Collagen Peptides

Protein intake is key for preserving muscle mass while losing weight. Collagen peptides are an easy way to boost daily protein without adding bulk to your diet. We use Wellgard Gold Standard Collagen Peptides — just one scoop stirred into morning coffee delivers over 11 g of protein and supports hair, skin and joints.

Daily Multivitamin

Even with a balanced diet, gaps can happen. A high-quality multivitamin helps cover the basics like Vitamin D, B vitamins and iron. We recommend Wellgard MyJourney Multivitamin which comes in capsule form and is taken with food at lunchtime for easy absorption.

Pumpkin Seed Oil + Saw Palmetto

Some people taking GLP-1 medication notice increased hair shedding during their weight-loss journey, which is why supplements that support hair health can be popular. Pumpkin seed oil and saw palmetto are often taken together for this reason, providing plant-based fatty acids that help maintain healthy hair growth. They are also widely used by men for urinary and prostate health, making them a versatile addition to a supplement routine. We like these Pumpkin Seed Oil + Saw Palmetto softgels that are simple to take with food as part of your daily plan.

Magnesium Glycinate

Magnesium is an essential mineral for relaxation, sleep quality and muscle function. Magnesium glycinate is a gentle, well-absorbed form often taken in the evening. We use Pure Nutrition MagG Magnesium Glycinate — two tablets before bed provide 200 mg of elemental magnesium and support a calmer night’s rest.

Final Thoughts

Adding supplements to your GLP-1 routine can make everyday life feel easier, but you don’t need to overload. Focus on the basics — hydration, protein, and key nutrients — and choose one or two options that fit your needs. Supplements should always complement your medication, not replace it, so check with your healthcare provider before adding anything new.

Quick Answers

Do I need supplements when taking GLP-1 medication like Mounjaro, Wegovy, or Ozempic?

No. Supplements are optional. Many people focus on the basics—hydration, adequate protein, and balanced meals—and then add targeted supplements only if needed. Always check with your healthcare professional before starting anything new.

Which electrolytes are most helpful for hydration on GLP-1s?

Look for a powder with sodium, potassium, and magnesium. These help maintain fluid balance and may reduce fatigue or light-headedness on lower-calorie days. Mix with water and sip through the day—especially if appetite is low.

Why do people take collagen peptides during weight loss?

Collagen peptides provide an easy protein boost that supports daily protein targets while appetite is reduced. Stir a scoop into coffee or smoothies to help maintain lean mass alongside a balanced diet.

When should I take a multivitamin?

Most multivitamins are best taken with food (often at lunch) to aid absorption and reduce the chance of stomach upset. Choose a quality formula that covers essentials like vitamin D, B vitamins, and iron (if appropriate for you).

What is magnesium glycinate good for—and when to take it?

Magnesium glycinate is a gentle, well-absorbed form that’s commonly used for muscle relaxation and sleep quality. Many people take 200–400 mg elemental magnesium in the evening, but confirm the right amount for you with a clinician.

Who might use pumpkin seed oil + saw palmetto?

People on a GLP-1 weight-loss journey sometimes take these supplements to support hair health, as hair shedding can occur with rapid weight loss. They are also commonly used by men to support urinary and prostate health. If you’re on prescription medicines or have a diagnosed condition, always check with your clinician before use.